Who is better, Sakura or Karin? In my opinion, Sakura in Naruto Shippuden does better because I knew her longer but in the long run they’re both still backstabbing fangirls who would drop his ass once he’s out of the room like Suigetsu said. Look at Sakura, she’s hitting on Naruto while Sasuke isnt there. Though obviously they’d be on him in a heartbeat if he was there.